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pentobarbital will reduce the level or effect of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.pentobarbital will reduce the level or impact of ibuprofen by impacting hepatic enzyme CYP2C9/ten metabolism. Minor/Importance Unidentified.pentobarbital will decrease the extent or effect of cinacalcet by influe